Navdeep Chandel, Ph.D., is an associate professor of molecular genetics and immunology at Northwestern University Feinberg School of Medicine. He has written the book Navigating Metabolism: A Primer for Clinicians about how to use metabolic pathways to treat disease.
Metabolism is an important process that all living organisms partake in. Metabolic pathways are responsible for generating energy, eliminating waste, and providing the fuel and building blocks needed for cells to grow and divide. In Navigating Metabolism, Navdeep Chandel takes readers on a journey through metabolism to better understand how it impacts our health and behavior.
Chandel presents the fundamentals of metabolism in a straightforward, accessible manner, starting with the different energy sources that power the metabolic pathways. He then looks at how the body leverages these energy sources to turn food into energy, which is vital for body functions including growth and repair. Through multiple examples of the different metabolic pathways, such as the citric acid cycle, Krebs cycle, glycolysis, and pentose phosphate pathways, Chandel further expands on how these pathways interact with each other and how they are used by the body to help maintain homeostasis.
Chandel explains how mutations in metabolic pathways can lead to disease. He uses the example of sickle cell anemia, a condition caused by a mutation in the globin gene, to show how changes to a metabolic pathway can affect health. He also looks at infections, nutrition, and inflammation and how they can all interact and alter metabolism.
The book additionally looks at how metabolism is affected by lifestyle, such as through exercise and diet. Chandel covers a variety of diets and preventive lifestyle approaches, such as intermittent fasting and the ketogenic diet. He also discusses the strategies and strategies that can be used to combat adverse metabolic symptoms, such as diet and lifestyle modifications, supplementation and drug therapies. With a valuable set of tools, the book provides readers with the resources they need to combat metabolic disorders and maintain optimal metabolic health.
Overall, Navdeep Chandel’s book Navigating Metabolism: A Primer for Clinicians is a valuable resource for clinicians, dietitians, and anyone interested in understanding how metabolic pathways operate and how they can be manipulated to help maintain optimal health. Through real-world examples and clear explanations, this book provides readers with the necessary tools and resources to combat metabolic disorders and maintain optimal metabolic health.
